Analysis of complete genome sequence of foot-and-mouth disease (FMD) Asia1 vaccine strain
نویسندگان
چکیده
منابع مشابه
Complete Genome Sequence of the Circulatory Foot-and-Mouth Disease Virus Serotype Asia1 in Bangladesh
The complete genome sequence of foot-and-mouth disease virus (FMDV) serotype Asia1 isolated from Bangladesh is reported here. Genome analysis revealed amino acid substitutions in the VP1 antigenic region and deletions in both the 5' and 3' untranslated regions (UTRs) compared to the genome of the existing vaccine strain (GenBank accession no. AY304994).
متن کاملComplete Genome Sequence Analysis of a Vaccine Strain of Foot-and-Mouth Disease Virus Serotype O from Pakistan
Sequencing and subsequent analysis of a vaccine strain of foot-and-mouth disease virus serotype O is reported here. Genomic heterogeneity in the protective epitopes (VP1 protein) of the reported strain, compared to characterized strains and available sequences from Pakistan, warrants further studies to determine vaccine-induced immunity and disease protection.
متن کاملPhylogenic analysis of serotype Asia1 foot-and-mouth disease virus from Sulaimani/Iraq using VP1 protein: heterogeneity with vaccine strain As1/Shamir/89
Foot-and-mouth disease virus (FMDV) serotypes O, A and Asia1 are responsible for a significant number of disease outbreaks in Iraq. The current study can be considered as the first molecular characterization of serotype Asia1 in Iraq. The present investigation reports the detection of serotype FMDV Asia1 from local farms in Sulaimani districts in 2012 and 2014 outbreaks. Phylogenetic analysis o...
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The foot-and-mouth disease virus (FMDV) afflicts livestock in more than 80 countries, limiting food production and global trade. Production of foot-and-mouth disease (FMD) vaccines requires cytosolic expression of the FMDV 3C protease to cleave the P1 polyprotein into mature capsid proteins, but the FMDV 3C protease is toxic to host cells. To identify less-toxic isoforms of the FMDV 3C protease...
متن کاملComplete Genome Sequence of Foot-and-Mouth Disease Virus Serotype O Strain YNTBa from Yunnan Province of China
YNTBa is a rabbit-passaged attenuated strain of foot-and-mouth disease virus (FMDV) serotype O. Here, we announce the complete genome sequence of YNTBa, which provides data for further studies on replication, virulence, its determinants, and cell and host tropism of YNTBa.
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ژورنال
عنوان ژورنال: Korean Journal of Veterinary Service
سال: 2011
ISSN: 1225-6552
DOI: 10.7853/kjvs.2011.34.2.095